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Renal Therapies

StatSeal helps STANDARDIZE, SIMPLIFY and MINIMIZE post procedure care and maintenance of renal therapy procedural sites. StatSeal’s ability to create an instant occlusive seal to stop bleeding, while stacking blood solids beneath make it an ideal pressure adjunct for achieving fast, consistent hemostasis following dialysis and other renal therapy procedures.

StatSeal Products for Renal Therapies

StatSeal topical dressing products are available in both powder and disc form to suit a wide variety of renal therapy applications. The discs are made from compressed powder encased in foam. Both powder products include an optional foam ring to contain the powder around the catheter site. All StatSeal products are non-systemic, hypoallergenic, have no age contraindications, and have passed all FDA-required biocompatibility testing.

Value Proposition

StatSeal use improves post-procedure site care for dialysis and renal patients by streamlining protocols, protecting access sites, and reducing rebleeds. StatSeal products work with any protein-rich body fluid to seal the access site, while stopping oozing and bleeding, improving patient recovery time and outcomes. Integrating StatSeal into renal therapy recovery protocols has been found to result in significant clinical, economical and operational efficiencies.

StatSeal products are comprised of a hydrophilic polymer and potassium ferrate. As a manual pressure adjunct, StatSeal products have a two-step mechanism of action that occurs simultaneously to instantly form a low pH occlusive seal or physical barrier over the wound site, letting nothing in or out.

The hydrophilic polymer rapidly dehydrates the blood and absorbs exudate, stacking up desiccated blood solids beneath to form a seal.

The potassium ferrate binds the blood solids and proteins together, adhering the seal to the wound to stop bleeding and oozing.

Beneath the seal, the pH is neutral and blood solids and proteins continue to stack naturally. Above the seal the hydrophilic polymer acts as a desiccant and creates an acidic environment with a pH of ~ 2.

On the right is a colorized microscopic image of the seal created by StatSeal. The catheter is purple, the blood components creating the seal are colored red and StatSeal powder is the brown substance directly over the seal.

Clinical Discussion & Messaging

StatSeal Applications for Renal Therapies

  • Fistuloplasty: Closure after sheath removal
  • Hemodialysis: Hemostasis after needle removal
  • Temporary & Long-Term Dialysis Catheters: Maintain a dry and intact insertion site

Clinical Benefits of StatSeal Use for Fistuloplasty and Hemodialysis Recovery

StatSeal offers several clinical benefits in the dialysis setting, particularly following fistuloplasty sheath removals or hemodialysis needle pulls. Its use can significantly reduce the duration and intensity of manual compression, decreasing hold times from ~20 minutes to less than 5 minutes. By avoiding excessive pressure and prolonged compression, StatSeal helps support improved vessel patency – a key point since “too long and too strong is wrong.” Importantly, StatSeal functions independently of the clotting cascade, making it an effective option for patients who are prone to bleeding. Once applied, the seal remains over the access site to help prevent rebleeding and naturally falls off as the wound heals. Additionally, StatSeal is hypoallergenic and non-systemic, meaning it does not enter the bloodstream, further enhancing its safety profile for repeated use in dialysis patients.
Significantly Accelerates Hemostasis
  • Reduces reliance on prolonged manual pressure
  • Works regardless of anticoagulation levels
Minimizes Post Procedure care
  • Reduces rebleeds and associated complications
  • Supports same-day discharge and shortens chair time
Improves Outcomes
  • Reduces clinician burden, time and costs
  • Improves patient throughput and scheduling efficiency

Clinical Benefits of StatSeal Dressings for Indwelling Dialysis Catheters

StatSeal topical dressing products offer a novel solution to help STANDARDIZE, SIMPLIFY and MINIMIZE post procedure care and maintenance of dialysis catheter insertion sites. StatSeal hemostatic dressings work independently of the clotting cascade to form an instant occlusive seal over catheter insertions that prevents oozing, bleeding, and dressing disruption by keeping sites dry and intact until the scheduled dressing change. Prophylactic use of StatSeal on catheter insertion has been shown to minimize dressing disruption, a known risk factor for infection, by effectively reducing exit site bleeding.

Creates an Instant Seal
  • Works with any protein-rich body fluid to prevent oozing and bleeding
  • Does not rely on clotting cascade – works for patients prone to bleeding
Minimizes Dressing Disruptions
  • Significantly reduces unplanned dressing changes
  • Keeps sites dry and intact, until the scheduled dressing change
Improves Outcomes
  • Controls catheter exit site bleeding
  • Improves delivery of atraumatic care and patient comfort

Selling Tools

TITLE: MKT-FORM-113.1-StatSeal for Renal Therapies
DESCRIPTION: This Renal Therapies sell sheet addresses the challenges of achieving hemostasis in renal therapy settings. It positions StatSeal as a reliable adjunct to manual pressure, accelerating hemostasis for therapies including hemodialysis, fistuloplasty, and dialysis catheter care. Clinical evidence and compelling visuals show how StatSeal reduces time to hemostasis—helping streamline post-procedure care and improve patient outcomes.

Videos

TITLE: MKT-VID-030.0-StatSeal Advanced Powder COVID-19+Patient
DESCRIPTION: StatSeal Powder application on Shiley dialysis catheter.

TITLE: MKT-VID-007.0-StatSeal Advanced Fistula Graft Sheath Removal (No Sound)
DESCRIPTION: An 0:53 second long video that shows StatSeal Advanced being used for a fistula graft sheath removal. The patient had received 2000 units of heparin. Hemostasis with the StatSeal Advanced Disc was obtained in 2 minutes.